Loss of heterozygosity LOH的意思|示意
杂合性缺失LOH
Loss of heterozygosity LOH的网络常见释义
杂合性丢失 Sozzi研究发现吸烟的肺鳞癌患者中80％(41／51)至少有一个FHIT位点的杂合性丢失(loss of heterozygosity LOH)，而非吸烟患者只有20％(9／40)，两组等位基因丢失率比较，具有统计学意义(P＝0.0001)，故认为FHIT基因是吸烟致肺癌的可疑靶点。
Loss of heterozygosity LOH相关例句
Methods We used the polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) to examine 40 oral squamous cell carcinomas for loss of heterozygosity (LOH) at APC.
方法应用聚合酶链反应限制性片段长度多态性分析方法(PCR - RFLP)对40例口腔鳞癌组织中apc基因的杂合缺失(LOH)进行检测。
Objective: To investigate the loss of heterozygosity (LOH) of ATM gene and BRCA2 gene and explore the relationship between two genes in patients with ALL and ANLL.
目的：探讨急性淋巴细胞白血病(all)与急性非淋巴细胞白血病(ANLL) AT M基因和BRCA2基因杂合性缺失及其相互关系。
Purpose To investigate the possible role of loss of heterozygosity (LOH) of tumor suppressor genes in the development of primary hepatic lymphoma (PHL).
目的探讨肿瘤抑制基因杂合性缺失(LOH)在肝原发性淋巴瘤(PHL)发生中的作用。
AIM: To examine the microsatellite instability (MSI) and loss of heterozygosity (LOH) in head and neck squamous cell carcinomas (HNSCC).
目的：探讨头颈部鳞癌的微卫星不稳定性(msi)及杂合性丢失(LOH)。
Pathology: p53 tumor suppressor gene mutation, loss of heterozygosity (LOH) at 11p15 locus. PAX-FKHR gene fusion.
病理学：p53肿瘤抑制基因突变，第11p15基因座杂和性丢失。