a sharp cookie的意思|示意

This person could be a sharp cookie or someone who is not easily fooled.

这种人可能会是“a sharp cookie(精明的人)”，他(她)很难被愚弄。

So I guess the first lesson here is when you make a bet with a sharp cookie (and Kevin is nothing if not razor sharp) you should define your terms carefully.

我想我们学到的第一课就是，如果你跟个很难搞的人打赌(Kevin最犀利不过了)，你应该谨慎自己的用词。

The neoplastic epithelial cells within the duct show minimal hyperchromatism and pleomorphism, but they have holes with sharp margins as though punched out by a cookie cutter.

导管内的肿瘤上皮细胞表现为淡染和多型现象，但是他们有边缘锐利的孔像被切饼机切过一样。