cross flow filtration的意思|示意

Cross flow filtration (also known as tangential flow filtration or TFF) is a type of membrane filtration used to separate suspended biomolecules, such as proteins, cells, and other macromolecules, from a solution. This process is done by passing a feed solution through the membrane, in which the liquid flows parallel to the membrane surface. The principle is that the solute molecules cannot pass through the membrane while the solvent molecules can. Consequently, a retentate (composed of undiluted solute and dilute solvent) is retained by the membrane while a permeate (consisting of dilute solute and undiluted solvent) is generated and passes through the membrane.

Cross flow filtration is a continuous process, which means there is no interruption in the feed solution. This makes it an efficient and cost-effective way to filter and concentrate macromolecules. It is commonly used in the biotechnology and pharmaceutical industries to purify proteins, cell cultures, and other biomolecules. It is also used to remove bacteria, debris, and other impurities from the product.

Cross flow filtration is a more effective filtration method than traditional filtration techniques. It is faster, more efficient, and does not require numerous filter changes and cleaning steps. This makes it an ideal choice for large-scale operations. Additionally, it generates fewer wastes and has a higher flux rate than other membrane-filtration techniques.

Overall, cross flow filtration is an effective and efficient method for separating and purifying suspended biomolecules from a solution. It is a cost-effective, continuous process that does not require multiple filter changes, making it an ideal choice for large-scale operations. Additionally, it generates fewer wastes than other filtration techniques and has a higher flux rate.