disease amyloid的意思|示意

Amyloid forms into big globules called plaques in the brain of Alzheimer's disease patients, and the same thing happens (more slowly) in everyone's brains.

淀粉体在老年痴呆症病人的脑中形成很大的、称为斑块的小球，同样的事情也发生在每个人的脑中(较慢而已)。

Traditional drug development in Alzheimer's disease is taking too narrow an approach by focusing intensively on the buildup of amyloid beta-protein in the brain, Dr. Nixon says.

传统的治疗老年痴呆症的药物研发思路仅仅集中在淀粉样β蛋白的累积上，Nixon博士说。

“In my view, the sweet spot for amyloid-lowering trials is mild Alzheimer’s disease, ” Dr. Selkoe said.

Selkoe还说：“在我看来，轻度老年痴呆症患者是降低淀粉样蛋白试验的最佳对象。”

This symposium deals with renal disease but it is appropriate to begin with a brief review of our present understanding of the nature of amyloid.

这篇综述是关于肾脏疾病的，但是不妨简单回顾一下我们目前对淀粉样蛋白的本质的了解。

Selkoe, D. J. , and D. Schenk. "Alzheimer's Disease: Molecular Understanding predicts Amyloid-based Therapeutics. " Annu Rev Pharmacol Toxicol. 43(2003): 545-84.

阿兹海莫症：以分子生物学领域的了解预测以类淀粉胜肽为基础的治疗〉《药理学与毒物学研究回顾杂志》 43（2003）： 545-84。

The disease begins, they believe, when for still unknown genetic and other reasons, the brain starts to churn out amyloid.

他们相信，疾病发生的初期，虽仍有未知的基因及其他原因在作祟，但脑部已经有大量的类乙型蛋白产生。